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Necrotizing granuloma

Granuloma

A granuloma is a clump of cells that forms when the immune system tries to fight off a harmful substance but cannot remove it from the body.

A necrotizing granuloma is an area of inflammation in which tissue has died. Necrotizing means dying or decaying.

Tuberculosis and granulomatosis with polyangiitis are conditions that cause necrotizing granulomas.

Open References

References

Jones KD, Urisman A. Histopathologic approach to the surgical lung biopsy in interstitial lung disease. In: Collard HR, Richeldi L, eds. Interstitial Lung Disease. Philadelphia, PA: Elsevier; 2018:chap 12.

 

Review Date: 7/1/2025

Reviewed By: Frank D. Brodkey, MD, FCCM, Associate Professor, Section of Pulmonary and Critical Care Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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